Betamethasone (Beta) and dexamethasone (Dex) are fluorinated chemical compounds that have been used since 1972 to reduce respiratory distress syndrome and mortality in women at risk of preterm birth. These chemicals are also used to treat allergic conditions, skin disorders, respiratory disorders and intestinal disorders. Dexamethasone is also used to treat certain types of cancer and sometimes cerebral edema.
The reason why betamethasone and dexamethasone molecules are preferred in the treatment is that these compounds cross the placenta to a large extent and reach the target fetal lung. The efficacy of both molecules in preventing preterm birth is very close to each other. Despite this, the use of betamethasone in treatment seems to be more effective recently. It is accepted that the half-life of the betamoson molecule in the maternal circulation is approximately 6 hours, and the half-life in the fetal circulation is approximately 12 hours.
Betamethasone and dexamethasone increase levels of steroids, usually produced by the adrenal gland (adrenal gland), they also tend to suppress the immune system. In general, betamethasone injection is recommended to promote fetal lung development in pregnancy complications with the danger of preterm delivery. This drug greatly increases the chances of survival. It reduces many of the risks associated with preterm birth by stimulating the rapid maturation of the lungs inside the fetus.
In short, betamethasone is a corticosteroid, that is, a man-made steroid similar to cortisol, a natural hormone produced by the adrenal gland.
Meanwhile, betamethasone is a steroid used to reduce inflammation in the horse's joints. It is not considered a performance enhancing drug. However, it gives an advantage to horses who do not feel the therapeutic effects during the race and do not have betamethasone in their system. In horse racing, betamethasone is an accepted and widely used drug. Injection of the drug into the joints relieves horses of discomfort by reducing inflammation, but there is some evidence to suggest that the substance masks injuries that would otherwise prevent an animal from racing, putting it at risk for further damage. therefore beAlthough tametasone is a legal drug, horses are not allowed on race day.
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