sildenafil, It is used to treat men with erectile dysfunction, that is, sexual impotence. Sildenafil type drugs prevent an enzyme called phosphodiesterase type-5 from working too fast. The penis is one of the areas where this enzyme works.
Erectile dysfunction is a condition in which the penis does not become erect and enlarge when a man is sexually excited or unable to maintain an erection. When a man is sexually aroused, his body's normal response is to increase blood flow to his penis to create an erection. The job of sildenafil is to help maintain an erection after touching the penis by controlling the enzyme. Sildenafil does not cause an erection without physical effects on the penis, such as those that occur during intercourse.
It is also used to treat symptoms of pulmonary arterial hypertension in both men and women. This is a type of high blood pressure that occurs between the heart and lungs. When hypertension occurs in the lungs, the heart must work harder to pump enough blood to the lungs. Sildenafil works on the phosphodiesterase type-5 enzyme in the lungs to relax blood vessels. This increases the blood supply to the lungs and reduces the workload of the heart.
In short, sildefanil is a drug used to relax the smooth muscle of the penis to increase blood flow and increase erection. It is a type of phosphodiesterase inhibitor. This drug is the active ingredient in viagra.
In the treatment of impotence, sildenafil works by inhibiting the effects of the phosphodiesterase type 5 enzyme. This enzyme is found inside the smooth muscle cell of certain blood vessels. It plays an important role in regulating blood flow to many parts of the body, including the soft erectile tissue inside the penis. When sexually aroused, the nervous system causes the muscles of the penis to relax, allowing blood to flow into the erectile tissue inside the penis. This is how hardening occurs. To maintain erection, a fibrous membrane contracts, trapping blood inside the penis and allowing the penis to remain rigid. Sildenafil improves blood flow to the penis by inhibiting the action of the phosphodiesterase type 5 enzyme and facilitates the achievement and maintenance of an erection when sexually aroused.
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