Injectable fillers are used in dermatology as a method to reconstruct facial deformities and repair the aging face. Although fillers have become a popular option among cosmetic patients, clinical experience has shown that fillers should be used with caution because complications can occur.
Fillers are products that are injected into soft tissue and are classified as either absorbable or non-absorbable (permanent). A variety of dermal and subcutaneous fillers are currently used for soft tissue augmentation.
While previously used filler materials were limited, those used today consist of a wide variety of substances such as collagen, hyaluronic acid, calcium hydroxylapatite, poly-l-lactic acid and synthetic or artificial polymers. The US Food and Drug Administration (FDA) has approved approximately 20 filler products for dermatological indications, each with unique properties, advantages, and disadvantages. For example, there are many fillers that not only provide soft tissue augmentation but also stimulate collagen production. However, complications can often occur years after initial treatment. Side effects such as swelling, erythema, and nodules may occur, and in rare cases, foreign body granulomas may develop and may be difficult to eliminate. In general, all fillers are foreign substances and therefore cause foreign body reactions, ranging from common ones, such as paraffin, to rare ones, such as hyaluronic acid. The clinical presentation of these reactions is variable, ranging from single or multiple nodules at the injection site to widespread, firm swelling of the face accompanied by skin redness.
As interest in an overall youthful appearance grows, there are increasingly more treatment options available to meet the demands of cosmetics in one of the fastest growing fields in dermatology. Fillers have also offered new options for patients who cannot afford plastic surgery or are sensitive to surgical intervention. The ideal filling material is non-allergenic, non-carcinogenic and non-teratogenic. These materials are stable, cost-effective, formable, recyclable and durable.
Meanwhile, the ideal filler should have predictable and consistent results, look natural, take little time to apply, require minimal preparation, create no patient downtime, and have a low risk of complications. The ideal application should be painless, user-friendly, and performed in an outpatient setting with minimal recovery and easy storage. However, no single filler is ideal for all patients, indications, and situations.
In short, efforts to design various fillers to ameliorate aging and volume loss are ongoing, and the science behind cosmetic injections is evolving.
Currently used fillers vary greatly in terms of their source, duration of activity and location of deposition. Indications for fillers include facial lines such as wrinkles and folds, lip plumping, facial deformations, sunken scars, sunken eyes, dermatological diseases, periocular melanosis (a cosmetic treatment involving the injection of vitamins, minerals and other substances into the skin around the eyes), scleroderma (thickening and thickening of the skin). hardening), earlobe plumping, earring sagging and neck décolletage rejuvenation.
The Cosmetic Practice Standards Agency (CPSA) is an organization that focuses on non-surgical cosmetic treatments such as fillers, skin rejuvenation, lasers and botulinum toxin injections. The “Dermal filler standards (fillers covering skin and soft tissue)” standard published by this organization defines the following:
given to businesses by our organization Among numerous testing, measurement, analysis and evaluation studies, there are also subcutaneous fillings testing and analysis services.