Skin Patch Test

Patch testing is a skin testing method used to find the cause of a possible allergic reaction on the skin. This reaction is called allergic contact dermatitis. Contact dermatitis is a reaction to something that comes into contact with the skin. Such allergic reactions often cause inflammation (redness and itching). Patch testing is done by the dermatology clinic. During patch testing, different substances are placed on the skin and taped in place. Patches are usually placed on the back, left for two days, and then removed. The tested skin area is evaluated by the dermatologist 2-4 days after the patches are removed.

Patch testing evaluates a slow, delayed skin reaction, so it is important that the patches remain in place. Additionally, the test area must be protected throughout the entire testing period.

If the skin is reacting to something and the dermatologist suspects that the skin is having an allergic reaction, a skin patch test is used to try to determine what caused the reaction. In fact, it is not easy to find the reasons for this. More than 15 thousand substances can cause allergic skin reactions. It is also possible to have an allergic reaction to more than one substance. That's why dermatologists recommend patch testing.

Patch testing is different from skin prick testing. A skin prick test or scratch test is used to check whether there is an immediate reaction on the skin. Skin allergies tend to develop over hours or days, so patch testing checks for this type of skin reaction.

The European Standard Series for patch test allergens includes the following allergens: Concentration percentage and source of dermatitis in petrolatum include:

• Potassium dichromate - 0,5 - Chromium (cement, shoes, metal)
• 4-Phenylenediamine base (PPD) - 1.0 - Hair dye
• Thiuram mixture - 1.0 - Rubber antioxidant
• Neomycin sulfate - 20.0 - Neomycin (antibiotic)
• Cobalt chloride - 1.0 - Cobalt (metal)
• Benzocaine - 5.0 - Benzocaine (local anesthetic)
• Nickel sulfate - 5.0 - Nickel (metal, coin, jewelry)
• Clioquinol (chinoform and vioform) - 5.0 - Clioquinol (antibacterial)
• Colophonium - 20.0 - Resin and colophony (adhesive)
• Paraben blend - 16.0 - Parabens (preservative)
• N-isopropyl-N-phenyl-4-phenylenediamine - 0,1 - Rubber antioxidant, leather shoes, oils and greases
• Lanolin alcohol - 30.0 - Wool fat
• Mercapto mix - 2.0 - Rubber antioxidant
• Epoxy resin - 1.0 - Epoxy resin (adhesive)
• Myroxylon pereirae resin - 25.0 - Peru Balsam (fragrance)
• 4-tert-Butylphenol formaldehyde resin - 1.0 - Para-tertiary butyl phenol-formaldehyde resin (adhesive)
• Mercaptobenzothiazole - 2.0 - Rubber antioxidant
• Formaldehyde - Water 2.0 - Formaldehyde and formalin (in clothing, cosmetics, household products)
• Fragrance blend (cinnamic alcohol, cinnamic aldehyde, hydroxycitronellal, amylcinnamaldehyde, geraniol, eugenol, isoeugenol, absolute oakmoss) - 8.0 (Sorbitan sesquioleate 5% emulsifier) ​​- Fragrance and perfume
• Sesquiterpene lactone mixture (alantolactone, dehydroxosus lactone, costunolide) - 0,1 - Compound allergy (daisies)
• Quaternium-15 (dowicil 200) - 1.0 - Quaternium-15 (preservative)
• Primin - 0,01 - Primula obconica (plant)
• Cl+Me-isothiazolinone (Kathon CG, 100 ppm) - 0,02 in water - Isothiazolinone (preservative)
• Budesonide - 0,01 - Topical corticosteroid - Positive patch test for budesonide
• Thixocortol pivalate - 0,1 - Topical corticosteroid
• Methyldibromo glutaronitrile - 0,5 - Formaldehyde-releasing preservative
• Methylisothiazolinone - 0,2 in water - Preservative
• Fragrance mix II - 14 - Fragrance and perfume
• Textile dye mixture - 6.6 - Textile dye

The European Standard Series is widely used in Europe and many other parts of the world. Other series include the International Standard Series, the TRUE® test series and the North American Standard Series.

given to businesses by our organization Among numerous testing, measurement, analysis and evaluation studies, there are also skin patch test services.