Fillers Content and Chemical Characterization Tests

Hyaluronic acid has important applications in orthopedics, ophthalmology and cosmetics. This polymer can be found in cosmetic products and is also used as a dermal filler. Fillers often contain cross-linked hyaluronic acid. Today's methods for measuring the amount of cross-linked hyaluronic acid are not very specific.

Some of the dermal fillers are naturally occurring and some are synthetically obtained from various substances. One of the most common compounds used in dermal fillers is hyaluronic acid. This compound plays an important role in keeping the skin moist and voluminous.

Among injectable subcutaneous fillers, structural fat grafts are considered the ideal filler. This oil is biocompatible, versatile, stable, long-lasting and natural-looking. In fact, the key to successful fat injection lies in technique. Harvesting, purifying, and transferring subcutaneous tissue to provide pure, intact fat parcels is essential for successful fat grafting. The surgeon must also infiltrate packets of refined fat into the recipient site so that they predictably and uniformly survive, integrate into host tissues, and achieve the desired structural change. The key to achieving these goals is to insert a very small amount of fatty tissue each time the infiltrating cannula is withdrawn. This maneuver maximizes the contact surface area between newly transplanted tissues and recipient tissues. Applying this technique to achieve structural volume change of the face can result in mild or dramatic improvements in patients' appearance.

Fat grafting is the safest of all fillers used. This method provides long-lasting and natural-looking structural changes in the hands of an experienced surgeon.

There are over twenty dermal fillers available in the United States today, with more on the way. There are currently hundreds of dermal fillers available in European, Asian and Middle Eastern countries. Although there are only a handful of FDA-approved dermal filler manufacturing companies in the United States, each company has a variety of product lines. These fillers are generally for superficial, medium and deep injections. Recently, these companies have begun to add fillers designed to treat specific areas of the face.

Dermal fillers are used in both men and women, in patients of all skin types and ethnicities, in various anatomical areas such as the chin, earlobes, temples, lips and veins, and patients are treated safely and effectively.

The rheological properties of dermal fillers vary depending on the viscosity, elasticity and stickiness of the dermal product. Viscosity and elasticity are measured by G exponent (G'). Dermal fillers with a high G' value are firmer and tend to maintain their shape. These products have a higher lifting capacity in facial rejuvenation.

In contrast, dermal fillers with a low G' value are thinner, more fluid and spread more easily. These are best for areas with fine lines, such as lines around the mouth or on the neck.

A dermal filler with high adhesion sticks together without spreading, but a filler with low adhesion sticks to the bone more easily.

It is important to understand the properties, ingredients and chemical characterization of the dermal filler to be used, but even more important is to understand the person's goals and the quality of their skin.

Whichever skin filler will be used, tests and analyzes to be carried out in advanced laboratories are extremely important to ensure that it is compatible with the person's body values.

given to businesses by our organization Among the numerous testing, measurement, analysis and evaluation studies, there are also filler content and chemical characterization testing services.