The physicochemical properties (physical and chemical characterizations) of biomaterials have a great influence on their interaction with cells, as well as play an important role on the in vivo performance of the materials.
Their physical characterization, i.e. internal microstructural properties of materials, includes the shape and size of particles, porosity, density and surface area. Chemical characterizations include determination of chemical composition and distribution of elements within the biomaterial.
In recent years, there have been innovations in tools for viewing and analyzing materials, and progress has been made in collecting and processing the results.
Different microscopic techniques, including optical and electron microscopy, applied to determine physical characterizations provide information from the atomic scale to the microscale and macroscale. Special samples are also used for specialized microscopic techniques such as scanning probe microscopy and atomic force microscopy. Surface characterization is performed using microscopic techniques. However, phase analysis techniques followed by microscopic techniques are controversial based on X-ray diffraction.
Infrared (IR) based spectroscopic characterization devices are used in analyzes to determine chemical characterizations. Especially size, shape, porosity, surface area and surface energy characterization are determined by this technique. In addition, particle size analysis is performed with dynamic light scattering (DLS). Contact angle measurement for surface energy, mercury intrusion porosimetry for analysis of pore structures, and gas adsorption measurements for surface area analysis are applied.
On the other hand, the physical and chemical characterization of membranes is very important in terms of morphology, thickness, grain size, and types and amounts of surface or grain boundary contamination. These properties can affect the performance of the membrane. Therefore, the information obtained by such analyzes is used to improve membrane performance during manufacture. Some of the most commonly used techniques in analysis are scanning electron microscopy, atomic force microscopy, X-ray diffraction technique, energy dispersive X-ray analysis, agar-electron spectroscopy, and thermal desorption spectroscopy. Also, since gas permeability depends on the thickness of the membrane, it is an important parameter to be characterized.
Our organization also provides physical and chemical characterization services with its trained and expert staff and advanced technological equipment, among the numerous test, measurement, analysis and evaluation studies it provides for businesses in various sectors.
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