Cytotoxicity is one of the most important indicators for biological evaluation in in vitro (out-of-body) studies. Cytotoxicity mainly refers to the rate of toxic effects on living cells. Cytotoxicity tests are the tests applied to evaluate the substance thought to be toxic in the appropriate cell culture, taking into account the rate of cell proliferation and its toxic effect on the cell.
-sitotoksisite-testleri.jpg "In Vitro Cytotoxicity Tests")
In vitro, chemical compounds such as drugs and pesticides have different systems of cytotoxicity, such as destruction of cell membranes, inhibition of protein synthesis, or irreversible binding to receptors. Reliable and reproducible short-term cytotoxicity and cell viability tests are needed to determine cell death caused by these damages. These tests are based on various cell functions.
Today, there is a wide range of cytotoxicity tests in the fields of toxicology and pharmacology. These tests are generally grouped as follows:
The important thing to obtain accurate and reliable results is to choose the most appropriate one among these tests. These tests also have to consider different parameters such as test compounds, detection system, specificity and sensitivity.
In the test, analysis, measurement and evaluation studies carried out in our organization, national and international standards and applicable legal regulations are complied with and reliable and impartial results are obtained. Among the numerous tests performed in this context, there are also in vitro cytotoxicity testing services.
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