The ASTM E1053-20 standard, developed by the American Society for Testing and Materials (ASTM), describes an application for evaluating the virucidal activity of liquid, aerosol or trigger spray microbicides intended for use on inanimate, non-porous environmental surfaces. This practice is used with most viruses grown in cultured cells. However, other host systems (e.g. embryonic eggs) are used with appropriate justification and documentation.
This practice should only be performed by persons trained in microbiological and virological techniques, in laboratories designed and equipped to work with infectious agents at the appropriate biosafety level. It is the research assistant's responsibility to determine if Good Laboratory Practices (GLP) regulations are required and to follow them as appropriate. It is necessary to apply to the appropriate regulatory agency for the performance standards of virucidal activity.
Briefly, this application is used to determine the effectiveness of liquid, aerosols/foams and trigger spray products against identified prototype viruses. The lot number of test substance and the number of replicates in each test are determined based on the target regulatory agency's requirements. Some regulatory bodies may require additional testing using other carrier tests for product registration purposes.
The antiviral activity of multiple disinfectant products is evaluated in laboratory-controlled tests. In the test method described in the ASTM E1053-20 standard, a non-porous glass or stainless steel carrier surface is inoculated with a liquid viral suspension and dried. The test product, trigger spray or foam prepared with an aerosol spray or dilution, is then applied to the carrier surface according to the manufacturer's instructions and incubated at room temperature and relative humidity for a certain contact time.
In advanced laboratories, two basic test methods are applied in this regard:
Our organization, with its trained and expert staff and advanced technological equipment, among the numerous test, measurement, analysis and evaluation studies it has given for businesses in various sectors, is within the scope of ASTM E1053-20 standard.It also provides standard testing services to evaluate the virucidal activity of chemicals intended for disinfection of immediate, non-porous environmental surfaces.
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