Toxicity tests are performed to evaluate the potential of a chemical or compound to cause harmful effects. Toxic assessment tests can be performed in research studies, on drugs containing impurities, on isolated impurities, or in air.
Air pollution is a global problem affecting people worldwide and impacting life in various ways. The pollutants released into the atmosphere are extremely diverse, and their toxicological characterization requires a complex approach and the use of modern methods. While the toxicity of some air pollutants has been addressed, others have not yet been sufficiently researched, and their toxicological properties remain unknown, for example, for nanoparticles. Furthermore, atmospheric pollutants consist of complex mixtures, and the effects of such mixtures cannot be determined solely through chemical analysis. Advanced laboratories are conducting studies to assess the toxic potential of compounds from atmospheric matrices.
Human cell-based in vitro tests have revealed that mixtures of both outdoor and indoor air pollutants interact with key cellular receptors, revealing various toxic potentials. Toxicity assessment tests show the relationship of toxic potentials to the fine particle structure and their bioaccessibility. People are exposed to very complex mixtures of pollutants outdoors and indoors, and some of these mixtures are evaluated as toxicological.
Although air pollution problems have been largely overcome in recent years, for example in European countries, there are still many places in the world where air pollution limits are frequently exceeded. In most cases, this pollution originates from heavy industry and traffic. One of the most important indicators of air quality is particulate matter concentration. Gaseous air pollutants also pose a health risk. Therefore, exposure to particulate matter in the environment is a significant human health problem, and PM10 (concentration of particles with an aerodynamic diameter smaller than 10 µm) is monitored.
Obviously, the chemical and toxicological evaluation is quite complementary. It is best to combine both data types. Chemical analyzes reveal the composition of the mixture and thus identify possible toxicity factors. The use of toxicological analyzes allows to cover the effects of the mixture and to identify the mechanisms of toxicity.
Our organization also provides toxic assessment testing services with its trained and expert staff and advanced technological equipment, among the numerous test, measurement, analysis and evaluation studies it provides for businesses in various sectors.
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